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Pif1 is a force-regulated helicase
Pif1 is a prototypical member of the 5′ to 3′ DNA helicase family conserved from bacteria to human. It has a high binding affinity for DNA, but unwinds double-stranded DNA (dsDNA) with a low processivity. Efficient DNA unwinding has been observed only at high protein concentrations that favor dimeri...
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| Udgivet i: | Nucleic Acids Res |
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| Main Authors: | , , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4872122/ https://ncbi.nlm.nih.gov/pubmed/27098034 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw295 |
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