G-quadruplex and G-rich sequence stimulate Pif1p-catalyzed downstream duplex DNA unwinding through reducing waiting time at ss/dsDNA junction

Alternative DNA structures that deviate from B-form double-stranded DNA such as G-quadruplex (G4) DNA can be formed by G-rich sequences that are widely distributed throughout the human genome. We have previously shown that Pif1p not only unfolds G4, but also unwinds the downstream duplex DNA in a G4...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Zhang, Bo, Wu, Wen-Qiang, Liu, Na-Nv, Duan, Xiao-Lei, Li, Ming, Dou, Shuo-Xing, Hou, Xi-Miao, Xi, Xu-Guang
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2016
Témata:
Nucleic Acid Enzymes
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5041479/
https://ncbi.nlm.nih.gov/pubmed/27471032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw669
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