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The mutation spectrum in genomic late replication domains shapes mammalian GC content
Genome sequence compositions and epigenetic organizations are correlated extensively across multiple length scales. Replication dynamics, in particular, is highly correlated with GC content. We combine genome-wide time of replication (ToR) data, topological domains maps and detailed functional epige...
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Опубликовано в: : | Nucleic Acids Res |
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Главные авторы: | , , , , , , |
Формат: | Artigo |
Язык: | Inglês |
Опубликовано: |
Oxford University Press
2016
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Предметы: | |
Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4872117/ https://ncbi.nlm.nih.gov/pubmed/27085808 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw268 |
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