The mutation spectrum in genomic late replication domains shapes mammalian GC content

Genome sequence compositions and epigenetic organizations are correlated extensively across multiple length scales. Replication dynamics, in particular, is highly correlated with GC content. We combine genome-wide time of replication (ToR) data, topological domains maps and detailed functional epige...

Full description

Saved in:
Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Kenigsberg, Ephraim, Yehuda, Yishai, Marjavaara, Lisette, Keszthelyi, Andrea, Chabes, Andrei, Tanay, Amos, Simon, Itamar
Format: Artigo
Language:Inglês
Published: Oxford University Press 2016
Subjects:
Genomics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4872117/
https://ncbi.nlm.nih.gov/pubmed/27085808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw268
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items