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Tat-dependent production of an HIV-1 TAR-encoded miRNA-like small RNA

Evidence is accumulating that retroviruses can produce microRNAs (miRNAs). To prevent cleavage of their RNA genome, retroviruses have to use an alternative RNA source as miRNA precursor. The transacting responsive (TAR) hairpin structure in HIV-1 RNA has been suggested as source for miRNAs, but how...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Autores principales: Harwig, Alex, Jongejan, Aldo, van Kampen, Antoine H. C., Berkhout, Ben, Das, Atze T.
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2016
Materias:
RNA
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4872094/
https://ncbi.nlm.nih.gov/pubmed/26984525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw167
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