Tat-dependent production of an HIV-1 TAR-encoded miRNA-like small RNA

Evidence is accumulating that retroviruses can produce microRNAs (miRNAs). To prevent cleavage of their RNA genome, retroviruses have to use an alternative RNA source as miRNA precursor. The transacting responsive (TAR) hairpin structure in HIV-1 RNA has been suggested as source for miRNAs, but how...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Harwig, Alex, Jongejan, Aldo, van Kampen, Antoine H. C., Berkhout, Ben, Das, Atze T.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2016
Fag:
RNA
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4872094/
https://ncbi.nlm.nih.gov/pubmed/26984525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw167
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