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Destabilization of the TAR hairpin affects the structure and function of the HIV-1 leader RNA
The TAR hairpin of the human immunodeficiency virus type 1 (HIV-1) RNA genome is essential for virus replication. TAR forms the binding site for the transcriptional trans-activator protein Tat and multiple additional TAR functions have been proposed. We previously constructed an HIV-1 variant in whi...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
2008
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2490758/ https://ncbi.nlm.nih.gov/pubmed/18586822 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn364 |
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