Destabilization of the TAR hairpin affects the structure and function of the HIV-1 leader RNA

The TAR hairpin of the human immunodeficiency virus type 1 (HIV-1) RNA genome is essential for virus replication. TAR forms the binding site for the transcriptional trans-activator protein Tat and multiple additional TAR functions have been proposed. We previously constructed an HIV-1 variant in whi...

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Bibliografiska uppgifter
Huvudupphovsmän: Vrolijk, Martine M., Ooms, Marcel, Harwig, Alex, Das, Atze T., Berkhout, Ben
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2008
Ämnen:
RNA
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2490758/
https://ncbi.nlm.nih.gov/pubmed/18586822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn364
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