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Mutations in the TAR hairpin affect the equilibrium between alternative conformations of the HIV-1 leader RNA

The HIV-1 untranslated leader RNA can adopt two mutually exclusive conformations that represent alternative secondary structures. This leader RNA can fold either an extended duplex through long-distance base pairing or a branched conformation in which the RNA locally folds into hairpin structures. B...

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Autori principali: Huthoff, Hendrik, Berkhout, Ben
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2001
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC55741/
https://ncbi.nlm.nih.gov/pubmed/11410668
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