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On the importance of the primer activation signal for initiation of tRNA(lys3)-primed reverse transcription of the HIV-1 RNA genome

Initiation of reverse transcription is a complex and regulated process in all retroviruses. Several base pairing interactions have been proposed to occur between the HIV-1 RNA genome and the specific tRNA(lys3) primer. The tRNA primer can form up to 21 bp with the primer binding site (PBS), and an a...

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Autores principales: Huthoff, Hendrik, Bugala, Katarzyna, Barciszewski, Jan, Berkhout, Ben
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2003
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC212812/
https://ncbi.nlm.nih.gov/pubmed/12930970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkg714
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