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More than 10% of yeast genes are related to genome stability and influence cellular senescence via rDNA maintenance
Genome instability triggers cellular senescence and is a common cause of cancer. The ribosomal RNA genes (rDNA), due to their repetitive structure, form a fragile site with frequent rearrangements. To identify eukaryotic factors that connect reduced genome stability to senescence we screened 4,876 s...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4872092/ https://ncbi.nlm.nih.gov/pubmed/26912831 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw110 |
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