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Rtt109 Prevents Hyper-Amplification of Ribosomal RNA Genes through Histone Modification in Budding Yeast

The genes encoding ribosomal RNA are the most abundant in the eukaryotic genome. They reside in tandem repetitive clusters, in some cases totaling hundreds of copies. Due to their repetitive structure, ribosomal RNA genes (rDNA) are easily lost by recombination events within the repeated cluster. We...

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Detalhes bibliográficos
Main Authors: Ide, Satoru, Saka, Kimiko, Kobayashi, Takehiko
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3616922/
https://ncbi.nlm.nih.gov/pubmed/23593017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003410
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