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Identification of a small-molecule ligand of the epigenetic reader protein Spindlin1 via a versatile screening platform
Epigenetic modifications of histone tails play an essential role in the regulation of eukaryotic transcription. Writer and eraser enzymes establish and maintain the epigenetic code by creating or removing posttranslational marks. Specific binding proteins, called readers, recognize the modifications...
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| Udgivet i: | Nucleic Acids Res |
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| Main Authors: | , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4872087/ https://ncbi.nlm.nih.gov/pubmed/26893353 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw089 |
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