ABCA7 frameshift deletion associated with Alzheimer disease in African Americans

OBJECTIVE: To identify a causative variant(s) that may contribute to Alzheimer disease (AD) in African Americans (AA) in the ATP-binding cassette, subfamily A (ABC1), member 7 (ABCA7) gene, a known risk factor for late-onset AD. METHODS: Custom capture sequencing was performed on ∼150 kb encompassin...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Neurol Genet
Main Authors: Cukier, Holly N., Kunkle, Brian W., Vardarajan, Badri N., Rolati, Sophie, Hamilton-Nelson, Kara L., Kohli, Martin A., Whitehead, Patrice L., Dombroski, Beth A., Van Booven, Derek, Lang, Rosalyn, Dykxhoorn, Derek M., Farrer, Lindsay A., Cuccaro, Michael L., Vance, Jeffery M., Gilbert, John R., Beecham, Gary W., Martin, Eden R., Carney, Regina M., Mayeux, Richard, Schellenberg, Gerard D., Byrd, Goldie S., Haines, Jonathan L., Pericak-Vance, Margaret A.
Format: Artigo
Jezik:Inglês
Izdano: Wolters Kluwer 2016
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4871806/
https://ncbi.nlm.nih.gov/pubmed/27231719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/NXG.0000000000000079
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki