Suppression of Cocaine-Evoked Hyperactivity by Self-Adjuvanting and Multivalent Peptide Nanofiber Vaccines

The development of anti-cocaine vaccines that counteract the rewarding effects of the drug are currently being investigated as adjunct therapies for prevention of relapse in abstinent users. However, cocaine is weakly immunogenic and requires conjugation to carrier proteins and coadministration with...

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Pubblicato in:ACS Chem Neurosci
Autori principali: Rudra, Jai S., Ding, Ye, Neelakantan, Harshini, Ding, Chunyong, Appavu, Rajagopal, Stutz, Sonja, Snook, Joshua D., Chen, Haiying, Cunningham, Kathryn A., Zhou, Jia
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4871789/
https://ncbi.nlm.nih.gov/pubmed/26926328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.5b00345
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