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A combined carrier-adjuvant system of peptide nanofibers and toll-like receptor agonists potentiates robust CD8+ T cell responses

Improving CD8+ T cell responses activated by subunit vaccination is crucial for improving vaccine efficacy and safety. Here we report a carrier-adjuvant system composed of self-assembling peptide nanofibers presenting an immunodominant antigen from herpes simplex virus (HSV) and toll-like receptor (...

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Detalhes bibliográficos
Publicado no:Vaccine
Main Authors: Rudra, Jai S., Banasik, Brianne N., Milligan, Gregg N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5769694/
https://ncbi.nlm.nih.gov/pubmed/29248267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2017.12.017
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