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Chloride Homeostasis Critically Regulates Synaptic NMDA Receptor Activity in Neuropathic Pain

Chronic neuropathic pain is a debilitating condition that remains difficult to treat. Diminished synaptic inhibition by GABA and glycine and increased NMDA receptor (NMDAR) activity in the spinal dorsal horn are key mechanisms underlying neuropathic pain. However, the reciprocal relationship between...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Li, Lingyong, Chen, Shao-Rui, Chen, Hong, Wen, Lei, Hittelman, Walter N., Xie, Jing-Dun, Pan, Hui-Lin
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4871741/
https://ncbi.nlm.nih.gov/pubmed/27160909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.04.039
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