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Chloride Homeostasis Critically Regulates Synaptic NMDA Receptor Activity in Neuropathic Pain

Chronic neuropathic pain is a debilitating condition that remains difficult to treat. Diminished synaptic inhibition by GABA and glycine and increased NMDA receptor (NMDAR) activity in the spinal dorsal horn are key mechanisms underlying neuropathic pain. However, the reciprocal relationship between...

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Podrobná bibliografie
Vydáno v:Cell Rep
Hlavní autoři: Li, Lingyong, Chen, Shao-Rui, Chen, Hong, Wen, Lei, Hittelman, Walter N., Xie, Jing-Dun, Pan, Hui-Lin
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4871741/
https://ncbi.nlm.nih.gov/pubmed/27160909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.04.039
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