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Bridging Mechanistic and Phenomenological Models of Complex Biological Systems

The inherent complexity of biological systems gives rise to complicated mechanistic models with a large number of parameters. On the other hand, the collective behavior of these systems can often be characterized by a relatively small number of phenomenological parameters. We use the Manifold Bounda...

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Veröffentlicht in:PLoS Comput Biol
Hauptverfasser: Transtrum, Mark K., Qiu, Peng
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4871498/
https://ncbi.nlm.nih.gov/pubmed/27187545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004915
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