Podocyte Depletion in Thin GBM and Alport Syndrome

The proximate genetic cause of both Thin GBM and Alport Syndrome (AS) is abnormal α3, 4 and 5 collagen IV chains resulting in abnormal glomerular basement membrane (GBM) structure/function. We previously reported that podocyte detachment rate measured in urine is increased in AS, suggesting that pod...

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Bibliographic Details
Published in:PLoS One
Main Authors: Wickman, Larysa, Hodgin, Jeffrey B., Wang, Su Q., Afshinnia, Farsad, Kershaw, David, Wiggins, Roger C.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2016
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4871445/
https://ncbi.nlm.nih.gov/pubmed/27192434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0155255
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