Urine Podocyte mRNAs, Proteinuria, and Progression in Human Glomerular Diseases

Model systems demonstrate that progression to ESRD is driven by progressive podocyte depletion (the podocyte depletion hypothesis) and can be noninvasively monitored through measurement of urine pellet podocyte mRNAs. To test these concepts in humans, we analyzed urine pellet mRNAs from 358 adult an...

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Hauptverfasser: Wickman, Larysa, Afshinnia, Farsad, Wang, Su Q., Yang, Yan, Wang, Fei, Chowdhury, Mahboob, Graham, Delia, Hawkins, Jennifer, Nishizono, Ryuzoh, Tanzer, Marie, Wiggins, Jocelyn, Escobar, Guillermo A., Rovin, Bradley, Song, Peter, Gipson, Debbie, Kershaw, David, Wiggins, Roger C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Nephrology 2013
Schlagworte:
Clinical Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3839551/
https://ncbi.nlm.nih.gov/pubmed/24052633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2013020173
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