Recapitulating adult human immune traits in laboratory mice by normalizing environment

Our current understanding of immunology was largely defined in laboratory mice because of experimental advantages including inbred homogeneity, tools for genetic manipulation, the ability to perform kinetic tissue analyses starting with the onset of disease, and tractable models. Comparably reductio...

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Pubblicato in:Nature
Autori principali: Beura, Lalit K., Hamilton, Sara E., Bi, Kevin, Schenkel, Jason M., Odumade, Oludare A., Casey, Kerry A., Thompson, Emily A., Fraser, Kathryn A., Rosato, Pamela C., Filali-Mouhim, Ali, Sekaly, Rafick P., Jenkins, Marc K., Vezys, Vaiva, Haining, W. Nicholas, Jameson, Stephen C., Masopust, David
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4871315/
https://ncbi.nlm.nih.gov/pubmed/27096360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature17655
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