Sequential infection with common pathogens promotes human-like immune gene expression and altered vaccine response

Immune responses differ between laboratory mice and humans. Chronic infection with viruses and parasites are common in humans, but are absent in laboratory mice, and thus represent potential contributors to inter-species differences in immunity. To test this, we sequentially infected laboratory mice...

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Udgivet i:Cell Host Microbe
Main Authors: Reese, Tiffany A., Bi, Kevin, Kambal, Amal, Filali-Mouhim, Ali, Beura, Lalit K., Bürger, Matheus C., Pulendran, Bali, Sekaly, Rafick, Jameson, Stephen C., Masopust, David, Haining, W. Nicholas, Virgin, Herbert W.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4896745/
https://ncbi.nlm.nih.gov/pubmed/27107939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2016.04.003
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