Sequential infection with common pathogens promotes human-like immune gene expression and altered vaccine response

Immune responses differ between laboratory mice and humans. Chronic infection with viruses and parasites are common in humans, but are absent in laboratory mice, and thus represent potential contributors to inter-species differences in immunity. To test this, we sequentially infected laboratory mice...

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Veröffentlicht in:Cell Host Microbe
Hauptverfasser: Reese, Tiffany A., Bi, Kevin, Kambal, Amal, Filali-Mouhim, Ali, Beura, Lalit K., Bürger, Matheus C., Pulendran, Bali, Sekaly, Rafick, Jameson, Stephen C., Masopust, David, Haining, W. Nicholas, Virgin, Herbert W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4896745/
https://ncbi.nlm.nih.gov/pubmed/27107939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2016.04.003
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