Effect of dehusked Garcinia kola seed on the overall pharmacokinetics of quinine in healthy Nigerian volunteers

We investigated the effect of concurrent ingestion of Garcinia kola seed on the pharmacokinetics of quinine. In a randomized crossover study, 24 healthy Nigerian volunteers were assigned into two groups (A and B; n = 12 per group) on the basis of G. kola dose orally ingested. Each subject received 6...

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Udgivet i:J Clin Pharmacol
Main Authors: Igbinoba, Sharon I., Onyeji, Cyprian O., Akanmu, Moses A., Soyinka, Julius O., Pullela, Srirama Sarma V.V, Cook, James M., Nathaniel, Thomas I.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4871276/
https://ncbi.nlm.nih.gov/pubmed/25328082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcph.414
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