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Effects of concurrent administration of nevirapine on the disposition of quinine in healthy volunteers
OBJECTIVES: Nevirapine and quinine are likely to be administered concurrently in the treatment of patients with HIV and malaria. Both drugs are metabolised to a significant extent by cytochrome P450 (CYP)3A4 and nevirapine is also an inducer of this enzyme. This study therefore evaluated the effect...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2752626/ https://ncbi.nlm.nih.gov/pubmed/19298689 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1211/jpp/61.04.0004 |
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