Pharmacokinetic interactions between ritonavir and quinine in healthy volunteers following concurrent administration

AIMS: To evaluate the pharmacokinetic interactions between ritonavir and quinine in healthy volunteers. METHODS: Ten healthy volunteers were each given 600-mg single oral doses of quinine alone, ritonavir alone (200 mg every 12 h for 9 days), and quinine in combination with ritonavir, in a three-per...

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Main Authors: Soyinka, Julius O, Onyeji, Cyprian O, Omoruyi, Sharon I, Owolabi, Adegbenga R, Sarma, Pullela V, Cook, James M
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Science Inc 2010
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Miscellaneous
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2829696/
https://ncbi.nlm.nih.gov/pubmed/20233197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2009.03566.x
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