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Effects of tetracycline on the pharmacokinetics of halofantrine in healthy volunteers

AIMS: To investigate the effect of tetracycline co-administration on the pharmacokinetics of halofantrine in healthy subjects. METHODS: Eight healthy males were each given 500 mg single oral doses of halofantrine alone, or with tetracycline (500 mg 12 hourly for 7 days), in a crossover fashion. Bloo...

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Détails bibliographiques
Auteurs principaux: Bassi, Peter U, Onyeji, Cyprian O, Ukponmwan, Otas E
Format: Artigo
Langue:Inglês
Publié: Blackwell Science Inc 2004
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1884545/
https://ncbi.nlm.nih.gov/pubmed/15206992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2004.02087.x
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