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Helicobacter pylori-induced Sonic Hedgehog expression is regulated by NFκB pathway activation: The use of a novel in vitro model to study epithelial response to infection

BACKGROUND: Helicobacter pylori (H. pylori) infection leads to acute induction of Sonic Hedgehog (Shh) in the stomach that is associated with the initiation of gastritis. The mechanism by which H. pylori induces Shh is unknown. Shh is a target gene of transcription factor Nuclear Factor-κB (NFκB). W...

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Détails bibliographiques
Publié dans:Helicobacter
Auteurs principaux: Schumacher, MA, Feng, R, Aihara, E, Engevik, AC, Montrose, MH, Ottemann, KM, Zavros, Y
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4871133/
https://ncbi.nlm.nih.gov/pubmed/25495001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/hel.12152
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