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Helicobacter pylori-induced Sonic Hedgehog expression is regulated by NFκB pathway activation: The use of a novel in vitro model to study epithelial response to infection

BACKGROUND: Helicobacter pylori (H. pylori) infection leads to acute induction of Sonic Hedgehog (Shh) in the stomach that is associated with the initiation of gastritis. The mechanism by which H. pylori induces Shh is unknown. Shh is a target gene of transcription factor Nuclear Factor-κB (NFκB). W...

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Bibliografiset tiedot
Julkaisussa:Helicobacter
Päätekijät: Schumacher, MA, Feng, R, Aihara, E, Engevik, AC, Montrose, MH, Ottemann, KM, Zavros, Y
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4871133/
https://ncbi.nlm.nih.gov/pubmed/25495001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/hel.12152
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