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Helicobacter pylori-induced Sonic Hedgehog expression is regulated by NFκB pathway activation: The use of a novel in vitro model to study epithelial response to infection

BACKGROUND: Helicobacter pylori (H. pylori) infection leads to acute induction of Sonic Hedgehog (Shh) in the stomach that is associated with the initiation of gastritis. The mechanism by which H. pylori induces Shh is unknown. Shh is a target gene of transcription factor Nuclear Factor-κB (NFκB). W...

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Detalhes bibliográficos
Publicado no:Helicobacter
Main Authors: Schumacher, MA, Feng, R, Aihara, E, Engevik, AC, Montrose, MH, Ottemann, KM, Zavros, Y
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4871133/
https://ncbi.nlm.nih.gov/pubmed/25495001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/hel.12152
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