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Gastric Sonic Hedgehog Acts as a Macrophage Chemoattractant During the Immune Response to Helicobacter pylori

BACKGROUND & AIMS: Macrophages mediate the epithelial response to Helicobacter pylori and are involved in the development of gastritis. Sonic Hedgehog (Shh) regulates gastric epithelial differentiation and function, but little is known about its immunoregulatory role in the stomach. We investiga...

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Autors principals: Schumacher, Michael A., Donnelly, Jessica M., Engevik, Amy C., Xiao, Chang, Yang, Li, Kenny, Susan, Varro, Andrea, Hollande, Frédéric, Samuelson, Linda C., Zavros, Yana
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3335966/
https://ncbi.nlm.nih.gov/pubmed/22285806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2012.01.029
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