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Sulfotransferase 1A1 Substrate Selectivity: A Molecular Clamp Mechanism
The human cytosolic sulfotransferases (SULTs) regulate hundreds, perhaps thousands, of small molecule metabolites and xenobiotics via transfer of a sulfuryl moiety (−SO(3)) from PAPS (3′-phosphoadenosine 5′-phosphosulfate) to the hydroxyls and primary amines of the recipients. In liver, where it is...
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| Veröffentlicht in: | Biochemistry |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4870834/ https://ncbi.nlm.nih.gov/pubmed/26340710 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.5b00406 |
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