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Design and Interpretation of Human Sulfotransferase 1A1 Assays

The human sulfotransferases (SULTs) regulate the activities of hundreds, if not thousands, of small molecule metabolites via transfer of the sulfuryl-moiety (-SO(3)) from the nucleotide donor, 3′-phosphoadenosine 5′-phosphosulfate (PAPS) to the hydroxyls and amines of the recipients. Our understandi...

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Détails bibliographiques
Publié dans:Drug Metab Dispos
Auteurs principaux: Wang, Ting, Cook, Ian, Leyh, Thomas S.
Format: Artigo
Langue:Inglês
Publié: The American Society for Pharmacology and Experimental Therapeutics 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4810762/
https://ncbi.nlm.nih.gov/pubmed/26658224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.115.068205
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