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A Nucleotide-Gated Molecular Pore Selects Sulfotransferase Substrates
Human SULT2A1 is one of two predominant sulfotransferases in liver and catalyzes transfer of the sulfuryl-moiety (-SO(3)) from activated sulfate (PAPS, 3′-phosphoadenosine 5-phosphosulfate) to hundreds of acceptors - metabolites and xenobiotics. Sulfation recodes the biologic activity of acceptors b...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3448010/ https://ncbi.nlm.nih.gov/pubmed/22703301 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi300631g |
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