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How should we measure proportionality on relative gene expression data?
Correlation is ubiquitously used in gene expression analysis although its validity as an objective criterion is often questionable. If no normalization reflecting the original mRNA counts in the cells is available, correlation between genes becomes spurious. Yet the need for normalization can be byp...
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| Publié dans: | Theory Biosci |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Springer Berlin Heidelberg
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4870310/ https://ncbi.nlm.nih.gov/pubmed/26762323 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12064-015-0220-8 |
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