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Suppression of STAT5b in pancreatic cancer cells leads to attenuated gemcitabine chemoresistance, adhesion and invasion

Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal solid malignancies, and there is an urgent need for new therapeutic strategies based on the molecular biology of PDAC. Signal transducers and activators of transcription 5 (STAT5) are known to be activated in a variety of malignancies...

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Bibliografske podrobnosti
izdano v:Oncol Rep
Main Authors: SUMIYOSHI, HIROKI, MATSUSHITA, AKIRA, NAKAMURA, YOSHIHARU, MATSUDA, YOKO, ISHIWATA, TOSHIYUKI, NAITO, ZENYA, UCHIDA, EIJI
Format: Artigo
Jezik:Inglês
Izdano: D.A. Spandidos 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4869940/
https://ncbi.nlm.nih.gov/pubmed/27035235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2016.4727
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