Suppression of STAT5b in pancreatic cancer cells leads to attenuated gemcitabine chemoresistance, adhesion and invasion

Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal solid malignancies, and there is an urgent need for new therapeutic strategies based on the molecular biology of PDAC. Signal transducers and activators of transcription 5 (STAT5) are known to be activated in a variety of malignancies...

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Vydáno v:Oncol Rep
Hlavní autoři: SUMIYOSHI, HIROKI, MATSUSHITA, AKIRA, NAKAMURA, YOSHIHARU, MATSUDA, YOKO, ISHIWATA, TOSHIYUKI, NAITO, ZENYA, UCHIDA, EIJI
Médium: Artigo
Jazyk:Inglês
Vydáno: D.A. Spandidos 2016
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Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4869940/
https://ncbi.nlm.nih.gov/pubmed/27035235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2016.4727
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