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Suppression of STAT5b in pancreatic cancer cells leads to attenuated gemcitabine chemoresistance, adhesion and invasion

Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal solid malignancies, and there is an urgent need for new therapeutic strategies based on the molecular biology of PDAC. Signal transducers and activators of transcription 5 (STAT5) are known to be activated in a variety of malignancies...

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Bibliographische Detailangaben
Veröffentlicht in:Oncol Rep
Hauptverfasser: SUMIYOSHI, HIROKI, MATSUSHITA, AKIRA, NAKAMURA, YOSHIHARU, MATSUDA, YOKO, ISHIWATA, TOSHIYUKI, NAITO, ZENYA, UCHIDA, EIJI
Format: Artigo
Sprache:Inglês
Veröffentlicht: D.A. Spandidos 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4869940/
https://ncbi.nlm.nih.gov/pubmed/27035235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2016.4727
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