Hedgehog signaling is a potent regulator of liver lipid metabolism and reveals a GLI-code associated with steatosis

Non-alcoholic fatty liver disease (NAFLD) is the most common liver disease in industrialized countries and is increasing in prevalence. The pathomechanisms, however, are poorly understood. This study assessed the unexpected role of the Hedgehog pathway in adult liver lipid metabolism. Using transgen...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Matz-Soja, Madlen, Rennert, Christiane, Schönefeld, Kristin, Aleithe, Susanne, Boettger, Jan, Schmidt-Heck, Wolfgang, Weiss, Thomas S, Hovhannisyan, Amalya, Zellmer, Sebastian, Klöting, Nora, Schulz, Angela, Kratzsch, Jürgen, Guthke, Reinhardt, Gebhardt, Rolf
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2016
Assuntos:
Biochemistry
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4869931/
https://ncbi.nlm.nih.gov/pubmed/27185526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.13308
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