Hedgehog signaling is a potent regulator of liver lipid metabolism and reveals a GLI-code associated with steatosis

Non-alcoholic fatty liver disease (NAFLD) is the most common liver disease in industrialized countries and is increasing in prevalence. The pathomechanisms, however, are poorly understood. This study assessed the unexpected role of the Hedgehog pathway in adult liver lipid metabolism. Using transgen...

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Dades bibliogràfiques
Publicat a:eLife
Autors principals: Matz-Soja, Madlen, Rennert, Christiane, Schönefeld, Kristin, Aleithe, Susanne, Boettger, Jan, Schmidt-Heck, Wolfgang, Weiss, Thomas S, Hovhannisyan, Amalya, Zellmer, Sebastian, Klöting, Nora, Schulz, Angela, Kratzsch, Jürgen, Guthke, Reinhardt, Gebhardt, Rolf
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications, Ltd 2016
Matèries:
Biochemistry
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4869931/
https://ncbi.nlm.nih.gov/pubmed/27185526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.13308
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