Hedgehog signaling is a potent regulator of liver lipid metabolism and reveals a GLI-code associated with steatosis

Non-alcoholic fatty liver disease (NAFLD) is the most common liver disease in industrialized countries and is increasing in prevalence. The pathomechanisms, however, are poorly understood. This study assessed the unexpected role of the Hedgehog pathway in adult liver lipid metabolism. Using transgen...

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Bibliographic Details
Published in:eLife
Main Authors: Matz-Soja, Madlen, Rennert, Christiane, Schönefeld, Kristin, Aleithe, Susanne, Boettger, Jan, Schmidt-Heck, Wolfgang, Weiss, Thomas S, Hovhannisyan, Amalya, Zellmer, Sebastian, Klöting, Nora, Schulz, Angela, Kratzsch, Jürgen, Guthke, Reinhardt, Gebhardt, Rolf
Format: Artigo
Language:Inglês
Published: eLife Sciences Publications, Ltd 2016
Subjects:
Biochemistry
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4869931/
https://ncbi.nlm.nih.gov/pubmed/27185526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.13308
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