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Proline-rich tyrosine kinase 2 downregulates peroxisome proliferator–activated receptor gamma to promote hypoxia-induced pulmonary artery smooth muscle cell proliferation

Abstract. Hypoxia stimulates pulmonary hypertension (PH), in part by increasing the proliferation of human pulmonary artery smooth muscle cells (HPASMCs) via sustained activation of mitogen-activated protein kinase, extracellular signal–regulated kinases 1 and 2 (ERK 1/2), and nuclear factor-kappa B...

詳細記述

保存先:
書誌詳細
出版年:Pulm Circ
主要な著者: Bijli, Kaiser M., Kang, Bum-Yong, Sutliff, Roy L., Hart, C. Michael
フォーマット: Artigo
言語:Inglês
出版事項: University of Chicago Press 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4869925/
https://ncbi.nlm.nih.gov/pubmed/27252847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/686012
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