A LAIR-1 insertion generates broadly reactive antibodies against malaria variant antigens

Plasmodium falciparum antigens expressed on the surface of infected erythrocytes are important targets of naturally acquired immunity against malaria, but their high number and variability provide the pathogen with a powerful means of escape from host antibodies(1–4). Although broadly reactive antib...

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發表在:Nature
Main Authors: Tan, Joshua, Pieper, Kathrin, Piccoli, Luca, Abdi, Abdirahman, Perez, Mathilde Foglierini, Geiger, Roger, Tully, Claire Maria, Jarrossay, David, Maina Ndungu, Francis, Wambua, Juliana, Bejon, Philip, Fregni, Chiara Silacci, Fernandez-Rodriguez, Blanca, Barbieri, Sonia, Bianchi, Siro, Marsh, Kevin, Thathy, Vandana, Corti, Davide, Sallusto, Federica, Bull, Peter, Lanzavecchia, Antonio
格式: Artigo
語言:Inglês
出版: 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4869849/
https://ncbi.nlm.nih.gov/pubmed/26700814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature16450
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