Serial image analysis of Mycobacterium tuberculosis colony growth reveals a persistent subpopulation in sputum during treatment of pulmonary TB

Faster elimination of drug tolerant ‘persister’ bacteria may shorten treatment of tuberculosis (TB) but no method exists to quantify persisters in clinical samples. We used automated image analysis to assess whether studying growth characteristics of individual Mycobacterium tuberculosis colonies fr...

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Bibliografiske detaljer
Udgivet i:Tuberculosis (Edinb)
Main Authors: Barr, David A., Kamdolozi, Mercy, Nishihara, Yo, Ndhlovu, Victor, Khonga, Margaret, Davies, Geraint R., Sloan, Derek J.
Format: Artigo
Sprog:Inglês
Udgivet: Churchill Livingstone 2016
Fag:
Drug Discovery and Resistance
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4869592/
https://ncbi.nlm.nih.gov/pubmed/27156626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tube.2016.03.001
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