Characterization of DNA methylation in Malawian Mycobacterium tuberculosis clinical isolates

BACKGROUND: Although Mycobacterium tuberculosis (Mtb) strains exhibit genomic homology of >99%, there is considerable variation in the phenotype. The underlying mechanisms of phenotypic heterogeneity in Mtb are not well understood but epigenetic variation is thought to contribute. At present the...

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Detalles Bibliográficos
Publicado en:PeerJ
Autores principales: Ndhlovu, Victor, Kiran, Anmol, Sloan, Derek J., Mandala, Wilson, Nliwasa, Marriott, Everett, Dean B., Kumwenda, Benjamin, Mwapasa, Mphatso, Kontogianni, Konstantina, Kamdolozi, Mercy, Corbett, Elizabeth, Caws, Maxine, Davies, Gerry
Formato: Artigo
Lenguaje:Inglês
Publicado: PeerJ Inc. 2020
Materias:
Genomics
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7749660/
https://ncbi.nlm.nih.gov/pubmed/33362962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.10432
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