Serial image analysis of Mycobacterium tuberculosis colony growth reveals a persistent subpopulation in sputum during treatment of pulmonary TB

Faster elimination of drug tolerant ‘persister’ bacteria may shorten treatment of tuberculosis (TB) but no method exists to quantify persisters in clinical samples. We used automated image analysis to assess whether studying growth characteristics of individual Mycobacterium tuberculosis colonies fr...

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Detalhes bibliográficos
Publicado no:Tuberculosis (Edinb)
Main Authors: Barr, David A., Kamdolozi, Mercy, Nishihara, Yo, Ndhlovu, Victor, Khonga, Margaret, Davies, Geraint R., Sloan, Derek J.
Formato: Artigo
Idioma:Inglês
Publicado em: Churchill Livingstone 2016
Assuntos:
Drug Discovery and Resistance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4869592/
https://ncbi.nlm.nih.gov/pubmed/27156626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tube.2016.03.001
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