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An allosteric role for receptor activity-modifying proteins in defining GPCR pharmacology
G protein-coupled receptors are allosteric proteins that control transmission of external signals to regulate cellular response. Although agonist binding promotes canonical G protein signalling transmitted through conformational changes, G protein-coupled receptors also interact with other proteins....
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| Udgivet i: | Cell Discov |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4869360/ https://ncbi.nlm.nih.gov/pubmed/27462459 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/celldisc.2016.12 |
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