The non-genomic loss of function of tumor suppressors: an essential role in the pathogenesis of chronic myeloid leukemia chronic phase

BACKGROUND: Chronic Myeloid Leukemia was always referred as a unique cancer due to the apparent independence from tumor suppressors’ deletions/mutations in the early stages of the disease. However, it is now well documented that even genetically wild-type tumor suppressors can be involved in tumorig...

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Veröffentlicht in:BMC Cancer
Hauptverfasser: Crivellaro, Sabrina, Carrà, Giovanna, Panuzzo, Cristina, Taulli, Riccardo, Guerrasio, Angelo, Saglio, Giuseppe, Morotti, Alessandro
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2016
Schlagworte:
Review
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4869339/
https://ncbi.nlm.nih.gov/pubmed/27184141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2346-6
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