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miR-216b regulation of c-Jun mediates GADD153/CHOP-dependent apoptosis
The ability of the unfolded protein response, UPR, to regulate cell homeostasis through both gene expression and protein synthesis has been well documented. One primary pro-apoptotic protein that responds to both PERK and Ire1 signalling is the CHOP/GADD153 transcription factor. Although CHOP defici...
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| Опубликовано в: : | Nat Commun |
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| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4869177/ https://ncbi.nlm.nih.gov/pubmed/27173017 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11422 |
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