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Effect of Catechol-O-methyltransferase-gene (COMT) Variants on Experimental and Acute Postoperative Pain in 1,000 Women undergoing Surgery for Breast Cancer

BACKGROUND: Catechol-O-methyltransferase (COMT) metabolizes catecholamines in different tissues. Polymorphisms in COMT gene can attenuate COMT activity and increase sensitivity to pain. Human studies exploring the effect of COMT polymorphisms on pain sensitivity have mostly included small, heterogen...

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Bibliografische gegevens
Gepubliceerd in:Anesthesiology
Hoofdauteurs: Kambur, Oleg, Kaunisto, Mari A., Tikkanen, Emmi, Leal, Suzanne M., Ripatti, Samuli, Kalso, Eija A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2013
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4869072/
https://ncbi.nlm.nih.gov/pubmed/24343288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0000000000000013
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